Important finding for the Phd candidate Amanda Rundblad at the Phd programmmes in health sciences and her coworkers that the intake of oxidised Fish oil (FO) and high-quality FO differently affect lipid composition in lipoprotein subclasses, with a more favourable effect mediated by high-quality FO. Their study presented in the publication “High-quality fish oil has a more favourable effect than oxidised fish oil on intermediate-density lipoprotein and LDL subclasses: a randomized controlled trial” is the first randomised controlled trial investigating the effects of supplementation with FO of different quality in healthy, normolipidaemic subjects on distribution and composition of lipoprotein subclasses measured with NMR spectroscopy.
The authors stated that FO supplementation reduces the risk of Cardiovascular disease (CVD.) However, it is not known if FO of different qualities have different effects on lipoprotein subclasses in humans. The aim of their project was to investigate the effects of oxidised FO and high-quality FO supplementation on lipoprotein subclasses and their lipid concentrations in healthy humans. Fifty-four subjects completed a double-blind randomised controlled intervention study. High-quality FO reduced the concentration of intermediate-density lipoprotein (IDL) particles and large, medium and small LDL particles, as well as the concentrations of total lipids, phospholipids, total cholesterol, cholesteryl esters and free cholesterol in IDL and LDL subclasses compared with oxidised FO and HOSO. Hence, high-quality FO and oxidised FO differently affect lipid composition in lipoprotein subclasses, with a more favourable effect mediated by high-quality FO. In future trials, reporting the oxidation levels of FO would be useful. The results from this study may indicate that FO with different qualities elicit different effects on blood lipids). The authors stated that a 10% reduction in LDL-cholesterol in 40-year-old men has been associated with a 54% reduced risk of ischaemic heart disease). Thus, their results on LDL-cholesterol might have a clinical relevance
The Phd candidate Anders Benteson Nygaard, at the PhD programme in Health Sciences, and his co-authors explores, for the first time, the bacterial composition of ventilation filter dust in Norwegian nurseries, and is important as it reveals what types of microorganisms nursery users are exposed to.
New publication- Associations between iodine intake from food during pregnancy and child neurodevelopment
Low intake of iodine in pregnant women is associated with poor language development, reduced fine motor development and behavioral problems when the child is three years according to a publication of the Ph.D candidate Marianne H Abel and her co-authors at the PhD programme in Health Sciences. The title of the publication is “Suboptimal Maternal Iodine Intake Is Associated with Impaired Child Neurodevelopment at 3 Years of Age in the Norwegian Mother and Child Cohort Study”.
Transitions of patients with traumatic brain injury and multiple trauma between specialized and municipal rehabilitation services—Professionals’ perspectives
In the recent publication PhD candidate Mirela lomic, and her coworkers stated that rehabilitation is a complex field requiring broad interprofessional and interorganizational collaboration. Patients with complex health conditions as traumatic brain injury (TBI) require care from multiple providers and are vulnerable to poorly executed transitions from one healthcare setting to another. The aim of the study was to explore rehabilitation professionals’ perspectives on interprofessional collaboration and coordination during transitions of patients with TBI and multiple trauma between specialized and municipal rehabilitation services.
CERQual’s assessment is an Approach to Assess Confidence in Findings from Qualitative Evidence Syntheses. CERQual’s assessment is of confidence for individual review findings from qualitative evidence syntheses is based on four components
(1) The methodological limitations of the qualitative studies contributing to a review finding,
(2) The relevance to the review question of the studies contributing to a review finding,
(3) The coherence of the review findings
(4) The adequacy of data supporting a review finding.
Anti-rheumatic treatment in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis: New publication from the PhD programme in health sciences
In the recent publication “Anti-rheumatic treatment is not associated with reduction of pentraxin 3 in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis” by the Phd candidate Gia Deyab and coworkers stated that Pentraxin 3 is proposed to be a marker of inflammation and cardiovascular risk, but its role in inflammatory rheumatic diseases is still uncertain. Their data do not support the notion that PTX3 might be a good biomarker for endothelial dysfunction and the associated cardiovascular risk.
Demographic projections in the Care Plan 2015 indicate that there are approximately 66,000 people with dementia in Norway and the number is expected to double by 2040. Dementia is receiving increasing attention from governments and politicians. Dementia is not a normal part of ageing, but old age is the primary risk factor for the disorder; without action, the prevalence dementias will increase substantially in the EU, and the cost of medical care and the societal burden of dementia will soon become unsustainable. Thus the clinicians’ different assessments of cognitive function are of importance. Through assessments, health professionals can measure cognitive function as well as get an understanding of how cognitive abilities contribute to and influence different performance in everyday life.
New publication from PhD program in health sciences of importance for documentation of changes in utilisation of antiepileptic drugs in epilepsy and non-epilepsy disorders
The candidate at the PhD programme in health sciences Arton Baftiu and his co authors have recently published “Changes in utilisation of antiepileptic drugs in epilepsy and non-epilepsy disorders—a pharmacoepidemiological study and clinical implications». According to the authors antiepileptic drugs (AEDs), and especially the newer drugs, are increasingly used in non-epilepsy indications, as in psychiatric disorders, neuropathic pain and migraine. PhD student Arton Baftiu and his co-authors stated that new patient groups are therefore exposed to AEDs.
New publication from Phd inn health Sciences of importance for explaining the initiation and progression of cancer?
The candidate at the PhD programme in health sciences Mrinal K. Das his co authors have recently published “Identification of Endogenous Controls for Use in miRNA Quantification in Human Cancer Cell Lines”.
The different types of cancer diseases are complex with many factors that can contribute to their development. Molecular and biogenetic studies on carcinogenesis and possible course of cancers have increased recently, and efforts are being exerted to develop treatment methods based on the results of such studies.
User involvement and experiential knowledge in interprofessional- A New publication from our PhD canditates
Person-centered care shifts focus away from the traditional biomedical model in favor of embracing personal choice and autonomy for people receiving health services. Much literature highlights the importance of incorporating an individual’s preferences,values, beliefs, and family or fictive kin into the decision making process related to daily life and care in clinical practice and in social service settings.